Antitrypanosomal agent 5

This small molecule is a potent and selective antitrypanosomal agent, exhibiting high activity against Trypanosoma brucei with an IC50 of 1 nM, while showing significantly lower cytotoxicity in mammalian HEK293 cells. It serves as a valuable research tool for studying trypanosome biology and for in vitro screening in the development of new therapeutics for African sleeping sickness.