CSF1R-IN-3
CSF1R-IN-3 is a potent and orally bioavailable CSF-1R inhibitor (IC50 = 2.1 nM) . It demonstrates anti-tumor activity in colorectal cancer models by suppressing macrophage migration and promoting M2-to-M1 repolarization, which enhances anti-tumor immunity in both cellular and animal studies.
Product Specifications
CAS Number
2760584-90-3
Product Name Alternative
CSF1R, CSF-1R, cFms, c-Fms
Field of Research
Signal Transduction
Purity
97.31% (May vary between batches)
Solubility
DMSO:56.2 mg/mL (97.8 mM)
Smiles
CN1CCN (CC (=O) Nc2c (C) [nH]c (\C=C3/C (=O) Nc4cc (NC (=O) Nc5cc (on5) C (C) (C) C) ccc34) c2C) CC1
Molecular Formula
C30H38N8O4
Molecular Weight
574.67
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
