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Afatinib oxalate

Afatinib oxalate is an irreversible, orally bioavailable dual inhibitor of EGFR and HER2. It potently inhibits various EGFR mutants and HER2, and is widely used in in vitro and in vivo research models for cancers such as non-small cell lung cancer, esophageal squamous cell carcinoma, and gastric cancer.

Product Specifications

CAS Number

1398312-64-5

Field of Research

Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Smiles

OC (=O) C (O) =O.OC (=O) C (O) =O.CN (C) C\C=C\C (=O) Nc1cc2c (Nc3ccc (F) c (Cl) c3) ncnc2cc1O[C@H]1CCOC1

Molecular Formula

C28H29ClFN5O11

Molecular Weight

666.01

Storage Conditions

-20°C

Notes

For research use only.

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