Afatinib oxalate
Afatinib oxalate is an irreversible, orally bioavailable dual inhibitor of EGFR and HER2. It potently inhibits various EGFR mutants and HER2, and is widely used in in vitro and in vivo research models for cancers such as non-small cell lung cancer, esophageal squamous cell carcinoma, and gastric cancer.
Product Specifications
CAS Number
1398312-64-5
Field of Research
Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Smiles
OC (=O) C (O) =O.OC (=O) C (O) =O.CN (C) C\C=C\C (=O) Nc1cc2c (Nc3ccc (F) c (Cl) c3) ncnc2cc1O[C@H]1CCOC1
Molecular Formula
C28H29ClFN5O11
Molecular Weight
666.01
Storage Conditions
-20°C
Notes
For research use only.
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