Integrase-LEDGF/p75 allosteric inhibitor 1
Integrase-LEDGF/p75 allosteric inhibitor 1 is an orally bioavailable small molecule that disrupts the HIV-1 IN-LEDGF/p75 protein-protein interaction. It potently blocks viral DNA integration, exhibiting antiviral activity with an EC50 of 3.9 nM against HIV-1 NL432 in cell-based assays, making it a valuable tool for studying lentiviral integration mechanisms.
Product Specifications
CAS Number
1431738-14-5
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry
Smiles
C (OC (C) (C) C) (C (O) =O) C1=C (C (C) =C (C (NS (C) (=O) =O) =C1C) C2=CC (C) =C (C) C=C2) C=3C (C) =C4C (=CC3) OCCC4
Molecular Formula
C33H41NO6S
Molecular Weight
579.75
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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