RET-IN-12
RET-IN-12 is a potent small molecule inhibitor targeting both wild-type RET and the V804M mutant, with IC50 values of 0.3 nM and 1 nM, respectively. It is a valuable research tool for investigating RET-driven oncogenesis in biochemical and cellular assays, supporting preclinical studies in cancer research.
Product Specifications
CAS Number
2684252-55-7
Field of Research
Cell Biology, Signal Transduction
Smiles
O (C) C1=CC2=C (C=C1OC) N=CC (=C2) C3=CC=C (CC (NC4=CC (C (NCCN (C) C) =O) =CC (C (F) (F) F) =C4) =O) C=N3
Molecular Formula
C30H30F3N5O4
Molecular Weight
581.59
Storage Conditions
-20°C
Notes
For research use only.
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