B-Raf IN 5
B-Raf IN 5 is a highly potent and selective B-Raf kinase inhibitor with an IC50 of 2.0 nM. It exhibits favorable metabolic stability and lacks PXR binding, making it a valuable chemical probe for investigating oncogenic B-Raf signaling in both cellular and animal models of cancer.
Product Specifications
CAS Number
2648698-30-8
Field of Research
Signal Transduction
Smiles
FC1=C (C2=C (SC (=N2) C3COCCN3) C4=NC (N) =NC=C4) C=C (Cl) C=C1NS (=O) (=O) C5=C (F) C=CC (F) =C5
Molecular Formula
C23H18ClF3N6O3S2
Molecular Weight
583.01
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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