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Sunvozertinib

Sunvozertinib (DZD9008) is a selective small molecule inhibitor targeting EGFR and Her2 mutations, including various exon 20 insertions and the L858R/T790M double mutation. It has demonstrated potent activity in preclinical in vitro and in vivo models of non-small cell lung cancer (NSCLC), supporting its investigation for targeted cancer therapy.

Product Specifications

CAS Number

2370013-12-8

Product Name Alternative

EGFR, DZD 9008, DZD9008, DZD-9008, BTK, Sunvozertinib

Field of Research

Cardiovascular Research, Signal Transduction

Purity

98.11% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8.56 mM) ; DMSO:247.5 mg/mL (423.74 mM)

Smiles

COc1cc (N2CC[C@H] (C2) N (C) C) c (NC (=O) C=C) cc1Nc1nccc (Nc2cc (Cl) c (F) cc2C (C) (C) O) n1

Molecular Formula

C29H35ClFN7O3

Molecular Weight

584.08

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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