FGFR-IN-8
FGFR-IN-8 is a potent, orally bioavailable inhibitor targeting wild-type and mutant FGFR isoforms with low nanomolar IC50 values. It induces apoptosis and demonstrates anti-tumor activity, supporting its use in preclinical cancer research for studying FGFR-driven malignancies in both cellular and animal models.
Product Specifications
CAS Number
2640217-64-5
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
N (C1=C (C=CC=N1) C=2N=C (NC3=CN (N=C3) C4CCN (C (C) C) CC4) N=CN2) C5=C (Cl) C (OC) =CC (OC) =C5Cl
Molecular Formula
C27H31Cl2N9O2
Molecular Weight
584.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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