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FGFR-IN-8

FGFR-IN-8 is a potent, orally bioavailable inhibitor targeting wild-type and mutant FGFR isoforms with low nanomolar IC50 values. It induces apoptosis and demonstrates anti-tumor activity, supporting its use in preclinical cancer research for studying FGFR-driven malignancies in both cellular and animal models.

Product Specifications

CAS Number

2640217-64-5

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

N (C1=C (C=CC=N1) C=2N=C (NC3=CN (N=C3) C4CCN (C (C) C) CC4) N=CN2) C5=C (Cl) C (OC) =CC (OC) =C5Cl

Molecular Formula

C27H31Cl2N9O2

Molecular Weight

584.5

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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