AChE/GSK-3β-IN-1
AChE/GSK-3β-IN-1 is a potent, brain-penetrant dual inhibitor of acetylcholinesterase (IC50: 1.2 nM) and glycogen synthase kinase-3β (IC50: 22.4 nM) . It demonstrates selectivity within the CMGC kinase family, reduces oxidative stress by inhibiting ROS, and is a valuable research tool for investigating Alzheimer's disease pathology in cellular and animal models.
Product Specifications
CAS Number
2412364-73-7
Field of Research
Neuroscience, Signal Transduction, Stem Cell & Developmental Biology
Smiles
N (CCNCC (NC1=CC (=CC=N1) C2=NC (OCC3CC3) =C (C (NC) =O) S2) =O) C4=C5C (=NC=6C4=CC=CC6) CCCC5
Molecular Formula
C31H35N7O3S
Molecular Weight
585.72
Storage Conditions
-20°C
Notes
For research use only.
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