RORγt/DHODH-IN-3
RORγt/DHODH-IN-3 ((S) -14d) is a potent, orally bioavailable dual inhibitor targeting RORγt and DHODH with IC50 values of 0.098 μM and 0.432 μM, respectively. It demonstrates significant anti-inflammatory activity in vivo, making it a valuable chemical probe for researching autoimmune diseases like psoriasis and multiple sclerosis in both cellular and animal models.
Product Specifications
Field of Research
Metabolism Research
Molecular Formula
C24H26ClF6N3O3S
Molecular Weight
585.99
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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