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EGFR-IN-18

EGFR-IN-18 is a potent small molecule inhibitor exhibiting low nanomolar activity against the triple mutant EGFR L858R/T790M/C797S (4.9 nM) and wild-type EGFR (47 nM) . This compound is a valuable research tool for investigating resistance mechanisms in non-small cell lung cancer and for preclinical in vitro studies targeting oncogenic EGFR variants.

Product Specifications

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Molecular Formula

C33H28N6O3S

Molecular Weight

588.68

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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