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BMS-378806

BMS-378806 (BMS-806) is a selective small-molecule inhibitor of the HIV-1 gp120-CD4 interaction, exhibiting antiviral activity with EC50 values ranging from 0.85 to 26.5 nM. It serves as a valuable research tool for studying viral entry mechanisms in vitro and for exploring novel therapeutic strategies against HIV-1 infection.

Product Specifications

CAS Number

357263-13-9

Product Name Alternative

CD4, CD4-gp120 interactions, BMS378806, BMS-378806, BMS806, BMS-806, BMS 806, BMS 378806, HIV Protease, HIV, HIVProtease, Inhibitor, Human immunodeficiency virus, gp120, inhibit

Field of Research

Immunology & Inflammation, Infectious Disease & Virology, Protein Biochemistry

Purity

99.31% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:3 mg/mL (7.38 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.12 mM) ; DMSO:81 mg/mL (199.3 mM)

Smiles

COc1ccnc2[nH]cc (C (=O) C (=O) N3CCN (C[C@H]3C) C (=O) c3ccccc3) c12

Molecular Formula

C22H22N4O4

Molecular Weight

406.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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