HP590
HP590 is a potent, orally bioavailable STAT3 inhibitor with IC50 values of 27.8 nM in a luciferase assay and 24.7 nM in an ATP inhibition assay. It demonstrates anti-proliferative and pro-apoptotic activity in gastric cancer cell lines, making it a valuable tool for oncology research targeting the STAT3 signaling pathway.
Product Specifications
CAS Number
2971855-37-3
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Smiles
O=C (N1CCN (CC2=CC=C (OCC (F) (F) F) C=C2) CC1) C3=CC=C (C4=NC (C5=CC=C (C (F) (F) F) C=C5) =NO4) C=C3
Molecular Formula
C29H24F6N4O3
Molecular Weight
590.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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