NNMT-IN-3
NNMT-IN-3 (compound 14) is a highly potent and selective nicotinamide N-methyltransferase (NNMT) inhibitor, demonstrating IC50 values of 1.1 nM in biochemical assays and 0.4 μM in cellular assays. This small molecule probe is a valuable research tool for investigating the role of NNMT in metabolic disorders, cancer biology, and age-related muscle wasting, with applications in both in vitro and in vivo studies.
Product Specifications
CAS Number
3031493-74-7
Field of Research
Signal Transduction
Smiles
ClC1=CC=C (CN2C3=CC=C (C) C=C3C=C2[C@@H]4N (C (C5=CC (C=C (C) N6) =C6N=C5) =O) C[C@@H] (N7C (CN) =CC (C) =N7) C4) C=C1
Molecular Formula
C34H34ClN7O
Molecular Weight
592.13
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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