FGFR3-IN-2
FGFR3-IN-2 (18b) is a selective small molecule inhibitor with high potency against FGFR3 (IC50 = 4.1 nM) and significantly lower activity against VEGFR2. This profile makes it a valuable research tool for investigating FGFR3-driven pathologies, such as certain cancers and skeletal dysplasias, in both cellular and animal models.
Product Specifications
CAS Number
2428742-58-7
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
O (CCN1CCOCC1) C2=C (C=CC (NC=3N=C (NC4=C (S (NCC) (=O) =O) C=CC=C4) N=CN3) =C2) N5CCN (C) CC5
Molecular Formula
C28H39N9O4S
Molecular Weight
597.73
Storage Conditions
-20°C
Notes
For research use only.
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