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Keap1-Nrf2-IN-1 TFA

Keap1-Nrf2-IN-1 TFA is a potent small molecule inhibitor of the Keap1-Nrf2 protein-protein interaction (IC50 = 43 nM) . It activates Nrf2-mediated cytoprotective pathways and has demonstrated protective effects against acetaminophen-induced hepatotoxicity in both cellular assays and animal studies.

Product Specifications

Field of Research

Cancer Biology; Immunology & Inflammation

Molecular Formula

C26H25F3N2O9S

Molecular Weight

598.54

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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