CDK4/6-IN-10

CDK4/6-IN-10 is a potent, orally bioavailable, and selective dual inhibitor of CDK4 (IC50=22 nM) and CDK6 (IC50=10 nM) . It demonstrates antitumor activity in preclinical models and is a candidate for research in oncology, particularly for studying multiple myeloma pathogenesis and therapy in vitro and in vivo.