KR-39038
KR-39038 is a potent and orally bioavailable GRK5 inhibitor (IC50 = 20 nM) that blocks the HDAC5 pathway. It demonstrates efficacy in cellular models by attenuating angiotensin II-induced hypertrophy in neonatal cardiomyocytes and shows potential for in vivo research in cardiac hypertrophy and heart failure studies.
Product Specifications
CAS Number
2770300-35-9
Field of Research
Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery
Smiles
O=C1N=C (NC2=CC (NCCCNCCCCNCCCN) =C (F) C=C12) C=3C=CC=CC3Cl
Molecular Formula
C24H32ClFN6O
Molecular Weight
475.00
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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