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KR-39038

KR-39038 is a potent and orally bioavailable GRK5 inhibitor (IC50 = 20 nM) that blocks the HDAC5 pathway. It demonstrates efficacy in cellular models by attenuating angiotensin II-induced hypertrophy in neonatal cardiomyocytes and shows potential for in vivo research in cardiac hypertrophy and heart failure studies.

Product Specifications

CAS Number

2770300-35-9

Field of Research

Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery

Smiles

O=C1N=C (NC2=CC (NCCCNCCCCNCCCN) =C (F) C=C12) C=3C=CC=CC3Cl

Molecular Formula

C24H32ClFN6O

Molecular Weight

475.00

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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