SEH inhibitor-1

SEH inhibitor-1 (TCPU) is a highly potent and orally bioavailable small molecule inhibitor of soluble epoxide hydrolase, demonstrating IC50 values of 0.4 nM (human) and 5.3 nM (murine) . This tool compound is widely used in preclinical research to investigate the role of sEH in cardiovascular, metabolic, and inflammatory diseases through both in vitro enzymatic assays and in vivo animal models.