Talotrexin ammonium
Talotrexin ammonium is a non-polyglutamatable antifolate that potently inhibits dihydrofolate reductase (DHFR) . Its mechanism of action has demonstrated anti-tumor efficacy in various in vitro and in vivo cancer models, making it a valuable research tool for oncology and enzymology studies.
Product Specifications
CAS Number
648420-92-2
Product Name Alternative
DHFR
Field of Research
Cell Biology, Metabolism Research, Molecular Biology
Purity
97.13% (May vary between batches)
Solubility
DMSO:50 mg/mL (84.66 mM)
Smiles
NC=1C2=C (N=CC (CNC3=CC=C (C (N[C@@H] (CCCNC (=O) C4=C (C (O) =O) C=CC=C4) C (O) =O) =O) C=C3) =N2) N=C (N) N1.N
Molecular Formula
C27H30N10O6
Molecular Weight
590.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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