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Talotrexin ammonium

Talotrexin ammonium is a non-polyglutamatable antifolate that potently inhibits dihydrofolate reductase (DHFR) . Its mechanism of action has demonstrated anti-tumor efficacy in various in vitro and in vivo cancer models, making it a valuable research tool for oncology and enzymology studies.

Product Specifications

CAS Number

648420-92-2

Product Name Alternative

DHFR

Field of Research

Cell Biology, Metabolism Research, Molecular Biology

Purity

97.13% (May vary between batches)

Solubility

DMSO:50 mg/mL (84.66 mM)

Smiles

NC=1C2=C (N=CC (CNC3=CC=C (C (N[C@@H] (CCCNC (=O) C4=C (C (O) =O) C=CC=C4) C (O) =O) =O) C=C3) =N2) N=C (N) N1.N

Molecular Formula

C27H30N10O6

Molecular Weight

590.59

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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