Deltarasin

Deltarasin is a potent small molecule inhibitor that disrupts the KRAS-PDEδ interaction by binding to PDEδ with a high affinity (Kd = 38 nM) . It is a valuable research tool for studying KRAS-driven cancers in both cellular and animal models, aiding in the exploration of oncogenic signaling and potential therapeutic strategies.

Product Specifications

CAS Number

1440898-61-2

Product Name Alternative

Ras, Phosphodiesterase (PDE), phosphodiesterase, Inhibitor, PDEδ, inhibit, Deltarasin

Field of Research

Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Purity

99.06% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:93 mg/mL (154.04 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.31 mM) ; DMSO:93 mg/mL (154.04 mM)