Deltarasin
Deltarasin is a potent small molecule inhibitor that disrupts the KRAS-PDEδ interaction by binding to PDEδ with a high affinity (Kd = 38 nM) . It is a valuable research tool for studying KRAS-driven cancers in both cellular and animal models, aiding in the exploration of oncogenic signaling and potential therapeutic strategies.
Product Specifications
CAS Number
1440898-61-2
Product Name Alternative
Ras, Phosphodiesterase (PDE), phosphodiesterase, Inhibitor, PDEδ, inhibit, Deltarasin
Field of Research
Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.06% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:93 mg/mL (154.04 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.31 mM) ; DMSO:93 mg/mL (154.04 mM)
Smiles
C (Oc1ccc (cc1) -c1nc2ccccc2n1Cc1ccccc1) [C@H] (C1CCNCC1) n1c (nc2ccccc12) -c1ccccc1
Molecular Formula
C40H37N5O
Molecular Weight
603.75
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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