MK-2048
MK-2048 is a potent small molecule inhibitor of HIV-1 integrase, demonstrating high in vitro potency with IC50 values of 2.6 nM against wild-type IN and 1.5 nM against the INR263K mutant. This compound is a valuable research tool for studying integrase function and resistance mechanisms in both biochemical and cell-based antiviral assays.
Product Specifications
CAS Number
869901-69-9
Field of Research
Infectious Disease & Virology, Protein Biochemistry
Smiles
C (NC) (=O) C=1C=2N3C (=C (O) C2C (=O) N (CC4=CC (Cl) =C (F) C=C4) N1) C (=O) N (CC) C[C@@H]3C
Molecular Formula
C21H21ClFN5O4
Molecular Weight
461.87
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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