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MK-2048

MK-2048 is a potent small molecule inhibitor of HIV-1 integrase, demonstrating high in vitro potency with IC50 values of 2.6 nM against wild-type IN and 1.5 nM against the INR263K mutant. This compound is a valuable research tool for studying integrase function and resistance mechanisms in both biochemical and cell-based antiviral assays.

Product Specifications

CAS Number

869901-69-9

Field of Research

Infectious Disease & Virology, Protein Biochemistry

Smiles

C (NC) (=O) C=1C=2N3C (=C (O) C2C (=O) N (CC4=CC (Cl) =C (F) C=C4) N1) C (=O) N (CC) C[C@@H]3C

Molecular Formula

C21H21ClFN5O4

Molecular Weight

461.87

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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