Ro 31-8220
Ro 31-8220 is a potent, cell-permeable bisindolylmaleimide compound acting as a broad-spectrum kinase inhibitor. It potently inhibits multiple PKC isoforms and other kinases like MAPKAP-K1b and GSK3β, making it a valuable tool for studying signal transduction in cellular and in vivo models of cancer and inflammation.
Product Specifications
CAS Number
125314-64-9
Field of Research
Epigenetics & Chromatin, Signal Transduction
Smiles
O=C1C (C=2C=3C (N (CCCSC (=N) N) C2) =CC=CC3) =C (C (=O) N1) C=4C=5C (N (C) C4) =CC=CC5
Molecular Formula
C25H23N5O2S
Molecular Weight
457.55
Storage Conditions
-20°C
Notes
For research use only.
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