Sabutoclax
Sabutoclax (BI-97C1) is a potent pan-inhibitor of anti-apoptotic Bcl-2 family proteins, including Bcl-xL, Bcl-2, Mcl-1, and Bfl-1. It has demonstrated pro-apoptotic activity in various cancer cell lines in vitro and has shown efficacy in xenograft tumor models in vivo, supporting its investigation in oncology research.
Product Specifications
CAS Number
1228108-65-3
Product Name Alternative
Bcl-2 Family, BI-97C1, Sabutoclax
Field of Research
Cell Biology
Purity
98.50% (May vary between batches)
Solubility
DMSO:93 mg/mL (132.71 mM) ;10% DMSO+90% Saline:3.3 mg/mL (4.71 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:22 mg/mL (31.39 mM)
Smiles
O=C (C1=C2C=C (C) [C@] ([C@]3=C (C) C=C4C (C (NC[C@H] (C) C5=CC=CC=C5) =O) =C (O) C (O) =CC4=C3O) =C (O) C2=CC (O) =C1O) NC[C@H] (C) C6=CC=CC=C6
Molecular Formula
C42H40N2O8
Molecular Weight
700.78
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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