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Sabutoclax

Sabutoclax (BI-97C1) is a potent pan-inhibitor of anti-apoptotic Bcl-2 family proteins, including Bcl-xL, Bcl-2, Mcl-1, and Bfl-1. It has demonstrated pro-apoptotic activity in various cancer cell lines in vitro and has shown efficacy in xenograft tumor models in vivo, supporting its investigation in oncology research.

Product Specifications

CAS Number

1228108-65-3

Product Name Alternative

Bcl-2 Family, BI-97C1, Sabutoclax

Field of Research

Cell Biology

Purity

98.50% (May vary between batches)

Solubility

DMSO:93 mg/mL (132.71 mM) ;10% DMSO+90% Saline:3.3 mg/mL (4.71 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:22 mg/mL (31.39 mM)

Smiles

O=C (C1=C2C=C (C) [C@] ([C@]3=C (C) C=C4C (C (NC[C@H] (C) C5=CC=CC=C5) =O) =C (O) C (O) =CC4=C3O) =C (O) C2=CC (O) =C1O) NC[C@H] (C) C6=CC=CC=C6

Molecular Formula

C42H40N2O8

Molecular Weight

700.78

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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