SB273005
SB273005 is a potent, orally bioavailable small molecule antagonist of integrins αvβ3 and αvβ5. It has demonstrated in vivo efficacy in murine pregnancy models by suppressing Th2 cell differentiation and IL-10 cytokine production, supporting its research use in immunology and reproductive studies.
Product Specifications
CAS Number
205678-31-5
Product Name Alternative
Integrin, SB 273005, SB273005, SB-273005, αVβ3 integrin, αVβ5 integrin
Field of Research
Immunology & Inflammation, Signal Transduction
Purity
99.58% (May vary between batches)
Solubility
Ethanol:10 mg/mL (22.15 mM) ; H2O:<1 mg/mL; DMSO:83 mg/mL (183.86 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.31 mM)
Smiles
C (C (O) =O) [C@@H]1CC=2C (CN (CC (F) (F) F) C1=O) =CC (OCCC=3N=C (NC) C=CC3) =CC2
Molecular Formula
C22H24F3N3O4
Molecular Weight
451.44
Storage Conditions
-20°C
Notes
For research use only.
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