Vinblastine
Vinblastine is a microtubule-disrupting agent that also inhibits nicotinic acetylcholine receptor (nAChR) activity with an IC50 of 8.9 μM. It is widely used in cancer research, particularly for studying mitotic arrest and apoptosis in both in vitro cell cultures and in vivo tumor models.
Product Specifications
CAS Number
865-21-4
Product Name Alternative
Vinblastine, nAChR, Microtubule Associated, MicrotubuleAssociated
Field of Research
Neuroscience, Pharmacology & Drug Discovery, Signal Transduction
Purity
97.42% (May vary between batches)
Solubility
DMSO:42 mg/mL (51.79 mM) ; Ethanol:6 mg/mL (7.4 mM)
Smiles
[H][C@@]12N3CC[C@@]11c4cc (c (OC) cc4N (C) [C@@]1 ([H]) [C@] (O) ([C@H] (OC (C) =O) [C@]2 (CC) C=CC3) C (=O) OC) [C@]1 (C[C@@]2 ([H]) CN (C[C@] (O) (CC) C2) CCc2c1[nH]c1ccccc21) C (=O) OC
Molecular Formula
C46H58N4O9
Molecular Weight
810.97
Storage Conditions
-20°C
Notes
For research use only.
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