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Vinblastine

Vinblastine is a microtubule-disrupting agent that also inhibits nicotinic acetylcholine receptor (nAChR) activity with an IC50 of 8.9 μM. It is widely used in cancer research, particularly for studying mitotic arrest and apoptosis in both in vitro cell cultures and in vivo tumor models.

Product Specifications

CAS Number

865-21-4

Product Name Alternative

Vinblastine, nAChR, Microtubule Associated, MicrotubuleAssociated

Field of Research

Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Purity

97.42% (May vary between batches)

Solubility

DMSO:42 mg/mL (51.79 mM) ; Ethanol:6 mg/mL (7.4 mM)

Smiles

[H][C@@]12N3CC[C@@]11c4cc (c (OC) cc4N (C) [C@@]1 ([H]) [C@] (O) ([C@H] (OC (C) =O) [C@]2 (CC) C=CC3) C (=O) OC) [C@]1 (C[C@@]2 ([H]) CN (C[C@] (O) (CC) C2) CCc2c1[nH]c1ccccc21) C (=O) OC

Molecular Formula

C46H58N4O9

Molecular Weight

810.97

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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