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WAY-600

WAY-600 is a potent and selective ATP-competitive mTOR inhibitor with an IC50 of 9 nM. It effectively suppresses both mTORC1 and mTORC2 signaling by inhibiting phosphorylation of S6K (T389) and AKT (S473), respectively, and demonstrates high selectivity over PI3K isoforms. This inhibitor is a valuable tool for studying mTOR-dependent pathways in cancer and metabolic disease research, applicable in both cellular and in vivo models.

Product Specifications

CAS Number

1062159-35-6

Product Name Alternative

Mammalian target of Rapamycin, Inhibitor, mTOR, inhibit, Src, WAY 600, PI3Kγ, PI3Kα, WAY600, WAY-600, VEGFR2

Field of Research

Cardiovascular Research, Signal Transduction

Purity

99.63% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.04 mM) ; Ethanol:2 mg/mL (4.04 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:45 mg/mL (90.98 mM)

Smiles

C (N1CCC (CC1) n1ncc2c (nc (nc12) -c1ccc2[nH]ccc2c1) N1CCOCC1) c1cccnc1

Molecular Formula

C28H30N8O

Molecular Weight

494.59

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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