WAY-600
WAY-600 is a potent and selective ATP-competitive mTOR inhibitor with an IC50 of 9 nM. It effectively suppresses both mTORC1 and mTORC2 signaling by inhibiting phosphorylation of S6K (T389) and AKT (S473), respectively, and demonstrates high selectivity over PI3K isoforms. This inhibitor is a valuable tool for studying mTOR-dependent pathways in cancer and metabolic disease research, applicable in both cellular and in vivo models.
Product Specifications
CAS Number
1062159-35-6
Product Name Alternative
Mammalian target of Rapamycin, Inhibitor, mTOR, inhibit, Src, WAY 600, PI3Kγ, PI3Kα, WAY600, WAY-600, VEGFR2
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.63% (May vary between batches)
Solubility
Smiles
C (N1CCC (CC1) n1ncc2c (nc (nc12) -c1ccc2[nH]ccc2c1) N1CCOCC1) c1cccnc1
Molecular Formula
C28H30N8O
Molecular Weight
494.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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