WYE-687
WYE-687 is a potent and selective ATP-competitive mTOR inhibitor with an IC50 of 7 nM. It effectively suppresses mTORC1 and mTORC2 signaling by inhibiting pS6K (T389) and pAKT (S473), respectively, while showing high selectivity over PI3K isoforms. This inhibitor is a valuable tool for studying mTOR-dependent pathways in cancer and metabolic disease research, both in vitro and in vivo.
Product Specifications
CAS Number
1062161-90-3
Product Name Alternative
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.98% (May vary between batches)
Solubility
H2O:60.2 mg/mL (113.88 mM) ; DMSO:60.2 mg/mL (113.88 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.78 mM)
Smiles
COC (=O) Nc1ccc (cc1) -c1nc (N2CCOCC2) c2cnn (C3CCN (Cc4cccnc4) CC3) c2n1
Molecular Formula
C28H32N8O3
Molecular Weight
528.61
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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