Gp120-α4β7 binding inhibitor 11
This small molecule inhibitor potently blocks the interaction between the HIV envelope glycoprotein gp120 and the α4β7 integrin receptor with an IC50 of 1.64 nM. It serves as a valuable research tool for investigating viral entry mechanisms and gut mucosal transmission in both cellular and animal models of HIV infection.
Product Specifications
CAS Number
869474-87-3
Product Name Alternative
Gp120-a4b7 binding inhibitor 11, gp120-alpha4beta7 binding inhibitor 11, gp120-α4β7 binding inhibitor 11, HIV Protease, HIV, HIVProtease, WAY659989
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry
Purity
97.61% (May vary between batches)
Solubility
DMSO:50 mg/mL (120.92 mM)
Smiles
C (C (NC1=C (C (NCC2=CC=C (C) C=C2) =O) C=CC=C1) =O) N3CC=4C (CC3) =CC=CC4
Molecular Formula
C26H27N3O2
Molecular Weight
413.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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