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PCSK9-IN-11

PCSK9-IN-11 is an orally active small molecule inhibitor of PCSK9 transcription, demonstrating an IC50 of 5.7 μM in HepG2 cells. By lowering PCSK9 levels, it upregulates hepatic LDL receptor protein, making it a useful research tool for investigating atherosclerosis and related cardiovascular diseases in both cellular and animal models.

Product Specifications

CAS Number

2882035-56-3

Product Name Alternative

PCSK9IN11, PCSK9-IN-11, PCSK9

Field of Research

Metabolism Research

Purity

98.37% (May vary between batches)

Solubility

DMSO:3.82 mg/mL (10.01 mM)

Smiles

O=C1C2=C (N=C (NCCO) N2CC=3C=CC=C (Cl) C3F) N (C (=O) N1C) C

Molecular Formula

C16H17ClFN5O3

Molecular Weight

381.789

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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