PCSK9-IN-11
PCSK9-IN-11 is an orally active small molecule inhibitor of PCSK9 transcription, demonstrating an IC50 of 5.7 μM in HepG2 cells. By lowering PCSK9 levels, it upregulates hepatic LDL receptor protein, making it a useful research tool for investigating atherosclerosis and related cardiovascular diseases in both cellular and animal models.
Product Specifications
CAS Number
2882035-56-3
Product Name Alternative
PCSK9IN11, PCSK9-IN-11, PCSK9
Field of Research
Metabolism Research
Purity
98.37% (May vary between batches)
Solubility
DMSO:3.82 mg/mL (10.01 mM)
Smiles
O=C1C2=C (N=C (NCCO) N2CC=3C=CC=C (Cl) C3F) N (C (=O) N1C) C
Molecular Formula
C16H17ClFN5O3
Molecular Weight
381.789
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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