DCeMM1
DCeMM1 is a molecular glue degrader that induces the CRL4DCAF15 E3 ligase to target and degrade the RNA-binding protein RBM39, as demonstrated by reduced RBM39 levels in WT KBM7 cells. This tool compound is used in vitro to study targeted protein degradation, splicing regulation, and cancer biology.
Product Specifications
CAS Number
118719-16-7
Product Name Alternative
Molecular Glues, MolecularGlues, dCeMM1
Field of Research
Pharmacology & Drug Discovery
Purity
99.29% (May vary between batches)
Solubility
DMSO:1.8 mg/mL (4.88 mM)
Smiles
Cc1ccc (cc1) S (=O) (=O) NN=Cc1cc (Br) ccc1O
Molecular Formula
C14H13BrN2O3S
Molecular Weight
369.23
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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