Trans-isrib A17
Trans-ISRIB A17 (ISR-IN-1) is a highly potent small molecule inhibitor of the integrated stress response (ISR), exhibiting an EC50 of 0.6 nM. It is widely used in both in vitro and in vivo research to study ISR pathway biology, cellular stress mechanisms, and potential therapeutic interventions for related diseases.
Product Specifications
CAS Number
1628478-15-8
Product Name Alternative
ISR-IN-1, trans-isrib A17
Field of Research
Immunology & Inflammation
Purity
98.17% (May vary between batches)
Solubility
DMSO:Slightly soluble
Smiles
O (CC (N[C@H]1CC[C@H] (NC (COC2=CC (F) =C (Cl) C=C2) =O) CC1) =O) C3=CC (F) =C (Cl) C=C3
Molecular Formula
C22H22Cl2F2N2O4
Molecular Weight
487.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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