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RBN-3143

RBN-3143 is a potent, NAD+-competitive PARP14 inhibitor (IC50= 4 nM) that blocks ADP-ribosylation and stabilizes the protein in cellular models. It shows research utility for studying PARP14's role in contexts such as lung inflammation, based on findings from in vitro and in vivo investigations.

Product Specifications

CAS Number

2360853-16-1

Product Name Alternative

PARP14, RBN3143, RBN-3143, RBN 3143

Field of Research

Epigenetics & Chromatin, Molecular Biology

Purity

98.64% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.45 mM) ; DMSO:11.2 mg/mL (24.91 mM)

Smiles

CC (=O) N1CCC (COc2cc (F) c3c (c2) nc (CSC2CCOCC2) [nH]c3=O) CC1

Molecular Formula

C22H28FN3O4S

Molecular Weight

449.54

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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