RBN-3143
RBN-3143 is a potent, NAD+-competitive PARP14 inhibitor (IC50= 4 nM) that blocks ADP-ribosylation and stabilizes the protein in cellular models. It shows research utility for studying PARP14's role in contexts such as lung inflammation, based on findings from in vitro and in vivo investigations.
Product Specifications
CAS Number
2360853-16-1
Product Name Alternative
PARP14, RBN3143, RBN-3143, RBN 3143
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
98.64% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.45 mM) ; DMSO:11.2 mg/mL (24.91 mM)
Smiles
CC (=O) N1CCC (COc2cc (F) c3c (c2) nc (CSC2CCOCC2) [nH]c3=O) CC1
Molecular Formula
C22H28FN3O4S
Molecular Weight
449.54
Storage Conditions
-20°C
Notes
For research use only.
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