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O-Desethyl Dapagliflozin

O-Desethyl Dapagliflozin (Empagliflozin-4) is an active metabolite and potent SGLT2 inhibitor with an IC50 of 33 nM. It is a valuable reference compound for pharmacokinetic and metabolic studies in diabetes research, applicable in both in vitro enzymatic assays and in vivo models.

Product Specifications

CAS Number

864070-37-1

Product Name Alternative

Empagliflozin-4, O-Desethyl Dapagliflozin, SGLT2

Field of Research

Pharmacology & Drug Discovery

Purity

97.09% (May vary between batches)

Solubility

DMSO:27.5 mg/mL (72.21 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (13.13 mM)

Smiles

O[C@H]1[C@@H] (O[C@H] (CO) [C@@H] (O) [C@@H]1O) C2=CC (CC3=CC=C (O) C=C3) =C (Cl) C=C2

Molecular Formula

C19H21ClO6

Molecular Weight

380.82

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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