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GSK-3β inhibitor 14

This compound, a 1,5-benzothiazepin-4 (5H) -one derivative, acts as a weak inhibitor of GSK-3β with an IC50 exceeding 100 μM. It serves as a useful research tool for investigating GSK-3β signaling pathways in cellular models of neurological disorders and diabetes.

Product Specifications

CAS Number

863004-48-2

Product Name Alternative

1,5-Benzothiazepin-4 (5H) -one, 2,3-dihydro-2-methyl-5- (phenylmethyl) -, GSK-3β inhibitor 14, GSK-3β, GSK-3beta inhibitor 14, GSK-3b inhibitor 14, GSK3

Field of Research

Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Purity

99.88% (May vary between batches)

Solubility

DMSO:2.88 mg/mL (10.16 mM)

Smiles

C (N1C=2C (SC (C) CC1=O) =CC=CC2) C3=CC=CC=C3

Molecular Formula

C17H17NOS

Molecular Weight

283.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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