Chaetocin
Chaetocin is a fungal metabolite and potent histone methyltransferase inhibitor, exhibiting IC50 values of 0.8 μM, 2.5 μM, and 3 μM against dSU (VAR) 3-9, mouse G9a, and DIM5, respectively. It is widely used in epigenetics research to probe histone methylation's role in gene silencing, cancer, and differentiation in both cellular and animal models.
Product Specifications
CAS Number
28097-03-2
Product Name Alternative
Neurospora crassa DIM5, Inhibitor, inhibit, HistoneMethyltransferase, Histone Methyltransferase, mouse G9a, Bacterial, Antibiotic, Chaetocin, dSU (VAR) 3-9
Field of Research
Cell Biology, Epigenetics & Chromatin
Purity
>98%
Bioactivity
Lysine methyltransferase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml) .
Smiles
CN1C (=O) C23CC4 (C (Nc5ccccc45) N2C (=O) C1 (CO) SS3) C12CC34SSC (CO) (N (C) C3=O) C (=O) N4C1Nc1ccccc21
Molecular Formula
C30H28N6O6S4
Molecular Weight
696.85
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
Isolated from Chaetomium species
Available Sizes
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