Chetomin
Chetomin is a potent small molecule inhibitor that disrupts the HIF-1α/HIF-2α-p300 interaction at low nanomolar concentrations, thereby attenuating HIF-1 transcriptional activity. It is widely used in hypoxia-related research, including studies on cancer biology and angiogenesis, in both cellular and animal models.
Product Specifications
CAS Number
1403-36-7
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Metabolism Research, Signal Transduction
Smiles
[H][C@]12Nc3ccccc3[C@]1 (C[C@]13SS[C@] (CO) (N (C) C1=O) C (=O) N23) n1cc (C[C@]23SS[C@] (CO) (N (C) C2=O) C (=O) N3C) c2ccccc12
Molecular Formula
C31H30N6O6S4
Molecular Weight
710.87
Storage Conditions
-20°C
Notes
For research use only.
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