PRT-060318
PRT-060318 (P142-76) is a potent and selective small molecule inhibitor of spleen tyrosine kinase (Syk) . It is used in research to investigate Syk-dependent pathways in vitro and has demonstrated efficacy in animal models of immune thrombosis, providing a tool for studying potential treatments for heparin-induced thrombocytopenia (HIT) .
Product Specifications
CAS Number
1194961-19-7
Product Name Alternative
PRT 060318, PRT 318, PRT060318, PRT-060318, PRT318, PRT-318, Syk, P142-76
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.82% (May vary between batches)
Solubility
H2O:5.6 mg/mL (16.45 mM)
Smiles
Cc1cccc (Nc2nc (N[C@@H]3CCCC[C@@H]3N) ncc2C (N) =O) c1
Molecular Formula
C18H24N6O
Molecular Weight
340.42
Storage Conditions
-20°C
Notes
For research use only.
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