Methylstat
Methylstat is a cell-permeable prodrug that, upon conversion to its free acid, acts as a broad-spectrum JMJD histone demethylase inhibitor. It demonstrates potent cellular activity, inhibiting cancer cell growth and inducing concentration-dependent histone hypermethylation, making it a valuable chemical probe for epigenetic research in oncology and molecular biology.
Product Specifications
CAS Number
1310877-95-2
Product Name Alternative
Apoptosis, anti-angiogenic, anti-proliferative, Inhibitor, HUVECs, HistoneDemethylase, Histone Demethylase, MDM-2/p53, G0/G1 phase, inhibit, JMJD2A, JMJD2C, JMJD2E, JMJD3, p53, low cytotoxicity, Methylstat, PHF8
Field of Research
Cell Biology, Epigenetics & Chromatin
Purity
98.34% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.96 mM) ; DMSO:25 mg/mL (49.45 mM)
Smiles
COC (=O) \C=C\C (=O) N (O) CCCCNCc1ccc (COC (=O) Nc2cccc3ccccc23) cc1
Molecular Formula
C28H31N3O6
Molecular Weight
505.56
Storage Conditions
-20°C
Notes
For research use only.
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