ML228
ML228 is a potent small molecule activator of the Hypoxia Inducible Factor (HIF) pathway with an EC50 of 1 μM. It effectively induces HIF signaling and its downstream target VEGF in vitro, making it a valuable research tool for studying hypoxia response, angiogenesis, and related disease models.
Product Specifications
CAS Number
1357171-62-0
Product Name Alternative
ML228, ML-228, ML 228, HIF
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Metabolism Research
Purity
99.03% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.81 mM) ; DMSO:150 mg/mL (361.02 mM)
Smiles
C (Nc1nc (nnc1-c1ccccc1) -c1ccccn1) c1ccc (cc1) -c1ccccc1
Molecular Formula
C27H21N5
Molecular Weight
415.49
Storage Conditions
-20°C
Notes
For research use only.
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