ML179
ML179 is a potent and selective inverse agonist targeting the nuclear receptor LRH-1 (NR5A2), exhibiting an IC50 of 320 nM. This small molecule is a valuable research tool for investigating LRH-1's role in metabolic regulation, stem cell biology, and cancer, facilitating both in vitro mechanistic studies and in vivo model research.
Product Specifications
CAS Number
1883548-87-5
Product Name Alternative
Inhibit, inverse, liver receptor homolog-1 (LRH1, NR5A2), ML179, ML-179, ML 179, ER-negative breast cancer, MCF-7, Inhibitor, C57Bl6 mice, SAA4, SAA1, probe compounds
Field of Research
Pharmacology & Drug Discovery
Purity
99.10% (May vary between batches)
Solubility
DMSO:4.25 mg/mL (10.06 mM)
Smiles
FC (F) (F) c1cccc (c1) N1CCN (CC1) c1cc (=O) n (C2CCCCC2) c (=O) [nH]1
Molecular Formula
C21H25F3N4O2
Molecular Weight
422.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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